Proinflammatory Cytokines: A Common Denominator in Depression and Somatic Symptoms?

Somatic symptoms in depression

Both painful and nonpainful somatic symptoms essentially characterize clinical states of depressive mood. So far, this well-established psychopathological knowledge has been appreciated only insufficiently by the official diagnostic systerms of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision (DSM-IV TR) and the ICD-10 Classification of Mental and Behavioral...

Depression and somatic symptoms scale: a new scale with both depression and somatic symptoms emphasized.

The authors' preliminary study selected 22 items for Depression and Somatic Symptoms Scale (DSSS), including depression subscale (DS) and somatic subscale (SS). The aim of the study was to test reliability and validity of the DSSS. The study enrolled 135 consecutive outpatients (34 male and 101 female) experiencing a major depressive episode (the MDE group), 95 of whom (25 male and 70 female) a...

[Somatic symptoms of depression].

OBJECTIVE The somatic component of depression is an important clinical phenomenon. The role of somatic amplification, alexithymia, anger and symptom attribution has been investigated in the genesis of the somatic symptoms of depression. METHOD The study was carried out with 32 patients attending the outpatient psychiatry clinics of Karadeniz Technical University Medical School, meeting the di...

Proinflammatory cytokines and sickness behavior: implications for depression and cancer-related symptoms.

PURPOSE/OBJECTIVES To review the relationship between proinflammatory cytokine release and resultant sickness behavior; to explore the implications of sickness behavior related to depression and cancer-related symptoms. DATA SOURCES Published articles and book chapters. DATA SYNTHESIS Proinflammatory cytokines (interleukin-1, interleukin-6, and tumor necrosis factor-alpha) are released as p...

Somatic Symptoms in Depression in Primary Care